A Non-Cell-Autonomous Mode of DNA Damage Response in Soma of <i>Caenorhabditis elegans</i>

A Non-Cell-Autonomous Mode of DNA Damage Response in Soma of <i>Caenorhabditis elegans</i>

Life has evolved a mechanism called DNA damage response (DDR) to sense, signal and remove/repair DNA damage, and its deficiency and dysfunction usually lead to genomic instability and development of cancer. The signaling mode of the DDR has been believed to be of cell-autonomy. However, the paradigm...

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Bibliographic Details
Main Authors: Zhangyu Dai, Wenjing Zhang, Mengke Shang, Huangqi Tang, Lijun Wu, Yuejin Wu, Ting Wang, Po Bian
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
DNA damage response
non-cell-autonomy
ionizing radiation
CPR-4
<i>C. elegans</i>
Online Access:https://www.mdpi.com/1422-0067/23/14/7544

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https://www.mdpi.com/1422-0067/23/14/7544

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