A perfusion-based three-dimensional cell culture system to model alveolar rhabdomyosarcoma pathological features

A perfusion-based three-dimensional cell culture system to model alveolar rhabdomyosarcoma pathological features

Abstract Although a rare disease, rhabdomyosarcoma (RMS) is one of the most common cancers in children the more aggressive and metastatic subtype is the alveolar RMS (ARMS). Survival outcomes with metastatic disease remain dismal and the need for new models that recapitulate key pathological feature...

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Bibliographic Details
Main Authors: Mattia Saggioro, Stefania D’Agostino, Giulia Veltri, Maira Bacchiega, Lucia Tombolan, Carlo Zanon, Piergiorgio Gamba, Valentina Serafin, Manuele Giuseppe Muraro, Ivan Martin, Michela Pozzobon
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-36210-4

Internet

https://doi.org/10.1038/s41598-023-36210-4

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