The P-body protein 4E-T represses translation to regulate the balance between cell genesis and establishment of the postnatal NSC pool

The P-body protein 4E-T represses translation to regulate the balance between cell genesis and establishment of the postnatal NSC pool

Summary: Here, we ask how developing precursors maintain the balance between cell genesis for tissue growth and establishment of adult stem cell pools, focusing on postnatal forebrain neural precursor cells (NPCs). We show that these NPCs are transcriptionally primed to differentiate and that the pr...

Full description

Bibliographic Details
Main Authors: Adelaida Kolaj, Siraj K. Zahr, Beatrix S. Wang, Taylor Krawec, Hilal Kazan, Guang Yang, David R. Kaplan, Freda D. Miller
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Cell Reports
Subjects:
CP: Stem cell research
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472300253X

Internet

http://www.sciencedirect.com/science/article/pii/S221112472300253X

Similar Items