Transcending frontiers in prostate cancer: the role of oncometabolites on epigenetic regulation, CSCs, and tumor microenvironment to identify new therapeutic strategies

Transcending frontiers in prostate cancer: the role of oncometabolites on epigenetic regulation, CSCs, and tumor microenvironment to identify new therapeutic strategies

Abstract Prostate cancer, as one of the most prevalent malignancies in males, exhibits an approximate 5-year survival rate of 95% in advanced stages. A myriad of molecular events and mutations, including the accumulation of oncometabolites, underpin the genesis and progression of this cancer type. D...

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Bibliographic Details
Main Authors: Giulia Ambrosini, Marco Cordani, Ali Zarrabi, Sergio Alcon-Rodriguez, Rosa M. Sainz, Guillermo Velasco, Pedro Gonzalez-Menendez, Ilaria Dando
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cell Communication and Signaling
Subjects:
Prostate cancer
Oncometabolites
Epigenetic alterations
Cancer stem cells (CSCs)
Metabolic Enzymes
EMT
Online Access:https://doi.org/10.1186/s12964-023-01462-0

Internet

https://doi.org/10.1186/s12964-023-01462-0

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