Mass Cytometry Analysis Reveals that Specific Intratumoral CD4+ T Cell Subsets Correlate with Patient Survival in Follicular Lymphoma

Mass Cytometry Analysis Reveals that Specific Intratumoral CD4+ T Cell Subsets Correlate with Patient Survival in Follicular Lymphoma

Summary: Follicular lymphoma (FL) is an indolent B cell malignancy characterized by an extensive but poorly functional T cell infiltrate in the tumor microenvironment. Using mass cytometry, we identified at least 12 subsets of intratumoral CD4+ T cells, 3 of which were unique to FL biopsies versus c...

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Bibliographic Details
Main Authors: Zhi-Zhang Yang, Hyo Jin Kim, Jose C. Villasboas, Tammy Price-Troska, Shahrzad Jalali, Hongyan Wu, Rebecca A. Luchtel, Mei-Yin C. Polley, Anne J. Novak, Stephen M. Ansell
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719301214

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http://www.sciencedirect.com/science/article/pii/S2211124719301214

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