Delayed and repeated intranasal delivery of bone marrow stromal cells increases regeneration and functional recovery after ischemic stroke in mice

Delayed and repeated intranasal delivery of bone marrow stromal cells increases regeneration and functional recovery after ischemic stroke in mice

Abstract Background Stroke is a leading cause of death and disability worldwide, yet there are limited treatments available. Intranasal administration is a novel non-invasive strategy to deliver cell therapy into the brain. Cells delivered via the intranasal route can migrate from the nasal mucosa t...

Full description

Bibliographic Details
Main Authors: Monica J. Chau, Todd C. Deveau, Xiaohuan Gu, Yo Sup Kim, Yun Xu, Shan Ping Yu, Ling Wei
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Neuroscience
Subjects:
Ischemic stroke
BMSC
Intranasal
Hypoxic preconditioning
Trophic factors
Online Access:http://link.springer.com/article/10.1186/s12868-018-0418-z

Internet

http://link.springer.com/article/10.1186/s12868-018-0418-z

Similar Items