Alginate-Based Carriers Loaded with Mulberry (<i>Morus alba</i> L.) Leaf Extract: A Promising Strategy for Prolonging 1-Deoxynojirimicyn (DNJ) Systemic Activity for the Nutraceutical Management of Hyperglycemic Conditions

Alginate-Based Carriers Loaded with Mulberry (<i>Morus alba</i> L.) Leaf Extract: A Promising Strategy for Prolonging 1-Deoxynojirimicyn (DNJ) Systemic Activity for the Nutraceutical Management of Hyperglycemic Conditions

The iminosugar 1-deoxynojirimicyn (DNJ) contained in mulberry leaves has displayed systemic beneficial effects against disorders of carbohydrate metabolism. Nevertheless, its effect is impaired by the short half-life. Alginate-based carriers were developed to encapsulate a DNJ-rich mulberry extract:...

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Bibliographic Details
Main Authors: Lucia Marchetti, Eleonora Truzzi, Maria Cecilia Rossi, Stefania Benvenuti, Silvia Cappellozza, Alessio Saviane, Luca Bogataj, Cristina Siligardi, Davide Bertelli
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Molecules
Subjects:
alginate
1-deoxynojirimicyn (DNJ)
NMR relaxation time constants
HPLC-MS
ATR-FTIR spectroscopy
swelling studies
Online Access:https://www.mdpi.com/1420-3049/29/4/797

Internet

https://www.mdpi.com/1420-3049/29/4/797

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