Somatic <it>VHL </it>gene alterations in MEN2-associated medullary thyroid carcinoma

<p>Abstract</p> <p>Background</p> <p>Germline mutations in <it>RET </it>are responsible for multiple endocrine neoplasia type 2 (MEN2), an autosomal dominantly inherited cancer syndrome that is characterized by medullary thyroid carcinoma (MTC), pheochromocy...

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Bibliographic Details
Main Authors: Pacak Karel, Zhuang Zhengping, Libutti Steven K, Tannapfel Andrea, Vortmeyer Alexander O, Brouwers Frederieke M, Koch Christian A, Neumann Hartmut PH, Paschke Ralf
Format: Article
Language:English
Published: BMC 2006-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/6/131