Optimal imaging time points considering accuracy and precision of Patlak linearization for 89Zr-immuno-PET: a simulation study

Optimal imaging time points considering accuracy and precision of Patlak linearization for 89Zr-immuno-PET: a simulation study

Abstract Purpose Zirconium-89-immuno-positron emission tomography (89Zr-immuno-PET) has enabled visualization of zirconium-89 labelled monoclonal antibody (89Zr-mAb) uptake in organs and tumors in vivo. Patlak linearization of 89Zr-immuno-PET quantification data allows for separation of reversible a...

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Bibliographic Details
Main Authors: Jessica E. Wijngaarden, Marc C. Huisman, Johanna E. E. Pouw, C. Willemien Menke-van der Houven van Oordt, Yvonne W. S. Jauw, Ronald Boellaard
Format: Article
Language:English
Published: SpringerOpen 2022-09-01
Series:EJNMMI Research
Subjects:
89Zr-immuno-PET
Patlak linearization
Monoclonal antibody
Molecular imaging
Online Access:https://doi.org/10.1186/s13550-022-00927-6

Internet

https://doi.org/10.1186/s13550-022-00927-6

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