Extracellular Vesicle-Based Communication May Contribute to the Co-Evolution of Cancer Stem Cells and Cancer-Associated Fibroblasts in Anti-Cancer Therapy

Extracellular Vesicle-Based Communication May Contribute to the Co-Evolution of Cancer Stem Cells and Cancer-Associated Fibroblasts in Anti-Cancer Therapy

Analogously to the natural selective forces in ecosystems, therapies impose selective pressure on cancer cells within tumors. Some tumor cells can adapt to this stress and are able to form resistant subpopulations, parallel with enrichment of cancer stem cell properties in the residual tumor masses....

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Bibliographic Details
Main Authors: Gábor Valcz, Edit I. Buzás, Anna Sebestyén, Tibor Krenács, Zoltán Szállási, Péter Igaz, Béla Molnár
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
extracellular vesicles
cancer stem cell
cancer cell-fibroblast interaction
therapy resistance
Online Access:https://www.mdpi.com/2072-6694/12/8/2324

Internet

https://www.mdpi.com/2072-6694/12/8/2324

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