A chemotaxis model to explain WHIM neutrophil accumulation in the bone marrow of WHIM mouse model

A chemotaxis model to explain WHIM neutrophil accumulation in the bone marrow of WHIM mouse model

Abstract. Neutrophils are essential immune cells that defend the host against pathogenic microbial agents. Neutrophils are produced in the bone marrow and are retained there through CXCR4–CXCL12 signaling. However, patients with the Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM)...

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Bibliographic Details
Main Authors: Ai Kia Yip, Akhila Balachander, Leonard D.L. Tan, Ka Hang Liong, Rui Zhen Tan, Karl Balabanian, Francoise Bachelerie, Lai Guan Ng, Keng-Hwee Chiam
Format: Article
Language:English
Published: Wolters Kluwer Health 2019-08-01
Series:Blood Science
Online Access:http://journals.lww.com/10.1097/BS9.0000000000000019

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http://journals.lww.com/10.1097/BS9.0000000000000019

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