TNFAIP3 Deficiency Affects Monocytes, Monocytes-Derived Cells and Microglia in Mice

TNFAIP3 Deficiency Affects Monocytes, Monocytes-Derived Cells and Microglia in Mice

The intracellular-ubiquitin-ending-enzyme tumor necrosis factor alpha-induced protein 3 (TNFAIP3) is a potent inhibitor of the pro-inflammatory nuclear factor kappa-light-chain-enhancer of activated B cell (NF-kB) pathway. Single nucleotide polymorphisms in TNFAIP3 locus have been associated to auto...

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Bibliographic Details
Main Authors: Francesca Montarolo, Simona Perga, Carlotta Tessarolo, Michela Spadaro, Serena Martire, Antonio Bertolotto
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
TNFAIP3
inflammation
myeloid cells
microglia
monocyte and macrophage
Online Access:https://www.mdpi.com/1422-0067/21/8/2830

Internet

https://www.mdpi.com/1422-0067/21/8/2830

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