Rapid PCR-Based Nanopore Adaptive Sequencing Improves Sensitivity and Timeliness of Viral Clinical Detection and Genome Surveillance

Rapid PCR-Based Nanopore Adaptive Sequencing Improves Sensitivity and Timeliness of Viral Clinical Detection and Genome Surveillance

Nanopore sequencing has been widely used for the real-time detection and surveillance of pathogens with portable MinION. Nanopore adaptive sequencing can enrich on-target sequences without additional pretreatment. In this study, the performance of adaptive sequencing was evaluated for viral genome e...

Full description

Bibliographic Details
Main Authors: Yanfeng Lin, Yan Dai, Yuqi Liu, Zhuli Ren, Hao Guo, Zhenzhong Li, Jinhui Li, Kaiying Wang, Lang Yang, Shuang Zhang, Hongbo Liu, Leili Jia, Ming Ni, Peng Li, Hongbin Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Microbiology
Subjects:
nanopore sequencing
adaptive sequencing
human adenovirus
SARS-CoV-2
pathogen detection
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.929241/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.929241/full

Similar Items