Alternative splicing of the SUMO1/2/3 transcripts affects cellular SUMOylation and produces functionally distinct SUMO protein isoforms

Alternative splicing of the SUMO1/2/3 transcripts affects cellular SUMOylation and produces functionally distinct SUMO protein isoforms

Abstract Substantial increases in the conjugation of the main human SUMO paralogs, SUMO1, SUMO2, and SUMO3, are observed upon exposure to different cellular stressors, and such increases are considered important to facilitate cell survival to stress. Despite their critical cellular role, little is k...

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Bibliographic Details
Main Authors: Myriah L. Acuña, Andrea García-Morin, Rebeca Orozco-Sepúlveda, Carlos Ontiveros, Alejandra Flores, Arely V. Diaz, Isabel Gutiérrez-Zubiate, Abhijeet R. Patil, Luis A. Alvarado, Sourav Roy, William K. Russell, Germán Rosas-Acosta
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-29357-7

Internet

https://doi.org/10.1038/s41598-023-29357-7

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