Local Accumulation of Lymphocytes in the Intima of Human Aorta Is Associated with Giant Multinucleated Endothelial Cells: Possible Explanation for Mosaicism of Atherosclerosis

Local Accumulation of Lymphocytes in the Intima of Human Aorta Is Associated with Giant Multinucleated Endothelial Cells: Possible Explanation for Mosaicism of Atherosclerosis

Distribution of different types of atherosclerotic lesions in the arterial wall is not diffuse, but is characterized by mosaicism. The causes of such distribution remain to be established. At the early stages of atherogenesis, low-density lipoprotein (LDL) particles and immune cells penetrate into t...

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Bibliographic Details
Main Authors: Nikita G. Nikiforov, Dmitry V. Zlenko, Varvara A. Orekhova, Alexandra A. Melnichenko, Alexander N. Orekhov
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
giant multinuclear endothelial cells
atherosclerosis
mosaicism
aortic intima
leukocytes
LDL
Online Access:https://www.mdpi.com/1422-0067/23/3/1059

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https://www.mdpi.com/1422-0067/23/3/1059

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