Vascular Senescence in Cardiovascular and Metabolic Diseases
In mammals, aging is associated with accumulation of senescent cells. Stresses such as telomere shortening and reactive oxygen species induce “cellular senescence”, which is characterized by growth arrest and alteration of the gene expression profile. Chronological aging is associated with developme...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-03-01
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Series: | Frontiers in Cardiovascular Medicine |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fcvm.2018.00018/full |