Vascular Senescence in Cardiovascular and Metabolic Diseases

In mammals, aging is associated with accumulation of senescent cells. Stresses such as telomere shortening and reactive oxygen species induce “cellular senescence”, which is characterized by growth arrest and alteration of the gene expression profile. Chronological aging is associated with developme...

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Bibliographic Details
Main Authors: Goro Katsuumi, Ippei Shimizu, Yohko Yoshida, Tohru Minamino
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fcvm.2018.00018/full