PI3K/AKT/mTOR Signaling Pathway in HPV-Driven Head and Neck Carcinogenesis: Therapeutic Implications

High-risk human papillomaviruses (HR-HPVs) are the causal agents of cervical, anogenital and a subset of head and neck carcinomas (HNCs). Indeed, oropharyngeal cancers are a type of HNC highly associated with HR-HPV infections and constitute a specific clinical entity. The oncogenic mechanism of HR-...

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Bibliographic Details
Main Authors: Francisco Aguayo, Francisco Perez-Dominguez, Julio C. Osorio, Carolina Oliva, Gloria M. Calaf
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/12/5/672