Microbubble formulation influences inflammatory response to focused ultrasound exposure in the brain

Abstract Focused ultrasound and microbubble (FUS + MB)-mediated blood–brain barrier (BBB) permeability enhancement can facilitate targeted brain-drug delivery. While controlling the magnitude of BBB permeability enhancement is necessary to limit tissue damage, little work has attempted to decouple t...

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Bibliographic Details
Main Authors: Dallan McMahon, Anne Lassus, Emmanuel Gaud, Victor Jeannot, Kullervo Hynynen
Format: Article
Language:English
Published: Nature Portfolio 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78657-9