NLRP6 is required for cancer-derived exosome-modified macrophage M2 polarization and promotes metastasis in small cell lung cancer

A schematic illustration showing that SCLC-derived exosomes polarize M2 macrophages to promote SCLC metastasis through the NLRP6/NF-κB pathway.

Bibliographic Details
Main Authors: Xinrui Rao, Xiaoshu Zhou, Geng Wang, Xiaohua Jie, Biyuan Xing, Yingzhuo Xu, Yunshang Chen, Jun Li, Kuikui Zhu, Zilong Wu, Gang Wu, Chuangyan Wu, Rui Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2022-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05336-0