Kinesin-5 Eg5 is essential for spindle assembly and chromosome alignment of mouse spermatocytes
Abstract Background Microtubule organization is essential for bipolar spindle assembly and chromosome segregation, which contribute to genome stability. Kinesin-5 Eg5 is known to be a crucial regulator in centrosome separation and spindle assembly in mammalian somatic cells, however, the functions a...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-03-01
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Series: | Cell Division |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13008-020-00063-4 |