Kinesin-5 Eg5 is essential for spindle assembly and chromosome alignment of mouse spermatocytes

Abstract Background Microtubule organization is essential for bipolar spindle assembly and chromosome segregation, which contribute to genome stability. Kinesin-5 Eg5 is known to be a crucial regulator in centrosome separation and spindle assembly in mammalian somatic cells, however, the functions a...

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Bibliographic Details
Main Authors: Zhen-Yu She, Ning Zhong, Kai-Wei Yu, Yu Xiao, Ya-Lan Wei, Yang Lin, Yue-Ling Li, Ming-Hui Lu
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Cell Division
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13008-020-00063-4