SETD2-dependent H3K36me3 plays a critical role in epigenetic regulation of the HPV31 life cycle.
The life cycle of HPV is tied to the differentiation status of its host cell, with productive replication, late gene expression and virion production restricted to the uppermost layers of the stratified epithelium. HPV DNA is histone-associated, exhibiting a chromatin structure similar to that of th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2018-10-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC6200281?pdf=render |