Using circulating microbial cell-free DNA to identify persistent Treponema pallidum infection in serofast syphilis patients
Summary: The question of whether serofast status of syphilis patients indicates an ongoing low-grade Treponema pallidum (T. pallidum) infection remains unanswered. To address this, we developed a machine learning model to identify T. pallidum in cell-free DNA (cfDNA) using next-generation sequencing...
Autori principali: | , , , , , , , , , |
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Natura: | Articolo |
Lingua: | English |
Pubblicazione: |
Elsevier
2024-04-01
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Serie: | iScience |
Soggetti: | |
Accesso online: | http://www.sciencedirect.com/science/article/pii/S2589004224006205 |