Using circulating microbial cell-free DNA to identify persistent Treponema pallidum infection in serofast syphilis patients

Using circulating microbial cell-free DNA to identify persistent Treponema pallidum infection in serofast syphilis patients

Summary: The question of whether serofast status of syphilis patients indicates an ongoing low-grade Treponema pallidum (T. pallidum) infection remains unanswered. To address this, we developed a machine learning model to identify T. pallidum in cell-free DNA (cfDNA) using next-generation sequencing...

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Bibliographic Details
Main Authors: Meng Yin Wu, Lu Chen, Li Cheng Liu, Ming Juan Liu, Yan Feng Li, He Yi Zheng, Ling Leng, Yi Jun Zou, Wei Jun Chen, Jun Li
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224006205

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http://www.sciencedirect.com/science/article/pii/S2589004224006205

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