Using circulating microbial cell-free DNA to identify persistent Treponema pallidum infection in serofast syphilis patients
Summary: The question of whether serofast status of syphilis patients indicates an ongoing low-grade Treponema pallidum (T. pallidum) infection remains unanswered. To address this, we developed a machine learning model to identify T. pallidum in cell-free DNA (cfDNA) using next-generation sequencing...
Main Authors: | , , , , , , , , , |
---|---|
格式: | Article |
語言: | English |
出版: |
Elsevier
2024-04-01
|
叢編: | iScience |
主題: | |
在線閱讀: | http://www.sciencedirect.com/science/article/pii/S2589004224006205 |