Dimerisation of HIV-2 genomic RNA is linked to efficient RNA packaging, normal particle maturation and viral infectivity

<p>Abstract</p> <p>Background</p> <p>Retroviruses selectively encapsidate two copies of their genomic RNA, the Gag protein binding a specific RNA motif in the 5' UTR of the genome. In human immunodeficiency virus type 2 (HIV-2), the principal packaging signal (Psi)...

Full description

Bibliographic Details
Main Authors: Crowther R Anthony, Greatorex Jane S, L'Hernault Anne, Lever Andrew ML
Format: Article
Language:English
Published: BMC 2007-12-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/4/1/90