Designing Stable <i>Bacillus anthracis</i> Antigens with a View to Recombinant Anthrax Vaccine Development

Designing Stable <i>Bacillus anthracis</i> Antigens with a View to Recombinant Anthrax Vaccine Development

Anthrax is a disease caused by <i>Bacillus anthracis</i> that affects mammals, including humans. Recombinant <i>B. anthracis</i> protective antigen (rPA) is the most common basis for modern anthrax vaccine candidates. However, this protein is characterised by low stability du...

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Bibliographic Details
Main Authors: Ekaterina M. Ryabchevskaya, Dmitriy L. Granovskiy, Ekaterina A. Evtushenko, Peter A. Ivanov, Olga A. Kondakova, Nikolai A. Nikitin, Olga V. Karpova
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Pharmaceutics
Subjects:
<i>Bacillus anthracis</i>
recombinant protective antigen
vaccines
stabilisation
structurally modified plant viruses
tobacco mosaic virus
Online Access:https://www.mdpi.com/1999-4923/14/4/806

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https://www.mdpi.com/1999-4923/14/4/806

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