Metabolomics and Lipidomics Reveal the Effect of Hepatic Vps33b Deficiency on Bile Acids and Lipids Metabolism

Metabolomics and Lipidomics Reveal the Effect of Hepatic Vps33b Deficiency on Bile Acids and Lipids Metabolism

Vascular protein sorting-associated protein 33B (VPS33B) plays important roles in hepatic polarity, which directly maintains the functional structure of the liver. It has reported that VPS33B has close association with arthrogryposis, renal dysfunction and cholestasis (ARC) syndrome. Unfortunately,...

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Bibliographic Details
Main Authors: Kaili Fu, Conghui Wang, Yue Gao, Shicheng Fan, Huizhen Zhang, Jiahong Sun, Yiming Jiang, Conghui Liu, Lihuan Guan, Junling Liu, Min Huang, Huichang Bi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Pharmacology
Subjects:
VPS33B
cholestasis
bile acids
metabolomics
lipidomics
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00276/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00276/full

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