Monosubstituted tricationic Zn(II) phthalocyanine enhances antimicrobial photodynamic inactivation (aPDI) of methicillin-resistant Staphylococcus aureus (MRSA) and cytotoxicity evaluation for topical applications: in vitro and in vivo study

Monosubstituted tricationic Zn(II) phthalocyanine enhances antimicrobial photodynamic inactivation (aPDI) of methicillin-resistant Staphylococcus aureus (MRSA) and cytotoxicity evaluation for topical applications: in vitro and in vivo study

ABSTRACTAntimicrobial photodynamic therapy (aPDT) is an innovative approach to combat multi-drug resistant bacteria. It is known that cationic Zn(II) phthalocyanines (ZnPc) are effective in mediating aPDT against methicillin-resistant Staphylococcus aureus (MRSA). Here we used ZnPc-based photosensit...

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Bibliographic Details
Main Authors: Priyanga Dharmaratne, Baiyan Wang, Roy C. H. Wong, Ben C. L. Chan, Kit-Man Lau, Mei-Rong Ke, Clara B. S. Lau, Dennis K. P. Ng, Kwok-Pui Fung, Margaret Ip
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
Subjects:
Methicillin-resistant
Staphylococcus aureus (MRSA)
antimicrobial photodynamic therapy (aPDT)
phthalocyanine
murine wound infection model
cytotoxicity
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1790305

Internet

https://www.tandfonline.com/doi/10.1080/22221751.2020.1790305

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