Caffeine-induced activated glucocorticoid metabolism in the hippocampus causes hypothalamic-pituitary-adrenal axis inhibition in fetal rats.

Caffeine-induced activated glucocorticoid metabolism in the hippocampus causes hypothalamic-pituitary-adrenal axis inhibition in fetal rats.

Epidemiological investigations have shown that fetuses with intrauterine growth retardation (IUGR) are susceptible to adult metabolic syndrome. Clinical investigations and experiments have demonstrated that caffeine is a definite inducer of IUGR, as children who ingest caffeine-containing food or dr...

Full description

Bibliographic Details
Main Authors: Dan Xu, Benjian Zhang, Gai Liang, Jie Ping, Hao Kou, Xiaojun Li, Jie Xiong, Dongcai Hu, Liaobin Chen, Jacques Magdalou, Hui Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3435254?pdf=render

Internet

http://europepmc.org/articles/PMC3435254?pdf=render

Similar Items