Ablation of the miRNA cluster 24 in cartilage and osteoblasts impairs bone remodeling

Abstract MicroRNAs (miRNAs) post-transcriptionally regulate cartilage and bone development and function, however, only few miRNAs have been described to play a role for cartilage to bone transition in vivo. Previously, we showed that cartilage-specific deletion of the Mirc24 cluster in newborn male...

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Bibliographic Details
Main Authors: Veronika S. Georgieva, Björn Bluhm, Kristina Probst, Mengjie Zhu, Juliane Heilig, Anja Niehoff, Bent Brachvogel
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-13231-z