Integrated radiogenomics models predict response to neoadjuvant chemotherapy in high grade serous ovarian cancer

Abstract High grade serous ovarian carcinoma (HGSOC) is a highly heterogeneous disease that typically presents at an advanced, metastatic state. The multi-scale complexity of HGSOC is a major obstacle to predicting response to neoadjuvant chemotherapy (NACT) and understanding critical determinants o...

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Bibliographic Details
Main Authors: Mireia Crispin-Ortuzar, Ramona Woitek, Marika A. V. Reinius, Elizabeth Moore, Lucian Beer, Vlad Bura, Leonardo Rundo, Cathal McCague, Stephan Ursprung, Lorena Escudero Sanchez, Paula Martin-Gonzalez, Florent Mouliere, Dineika Chandrananda, James Morris, Teodora Goranova, Anna M. Piskorz, Naveena Singh, Anju Sahdev, Roxana Pintican, Marta Zerunian, Nitzan Rosenfeld, Helen Addley, Mercedes Jimenez-Linan, Florian Markowetz, Evis Sala, James D. Brenton
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41820-7