Chromosomal Instability in Acute Myeloid Leukemia

Chromosomal Instability in Acute Myeloid Leukemia

Chromosomal instability (CIN), the increasing rate in which cells acquire new chromosomal alterations, is one of the hallmarks of cancer. Many studies highlighted CIN as an important mechanism in the origin, progression, and relapse of acute myeloid leukemia (AML). The ambivalent feature of CIN as a...

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Bibliographic Details
Main Authors: Mateus de Oliveira Lisboa, Paulo Roberto Slud Brofman, Ana Teresa Schmid-Braz, Aline Rangel-Pozzo, Sabine Mai
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
chromosomal instability
acute myeloid leukemia
cytogenetic heterogeneity
aneuploidy
complex karyotype
<i>TP53</i>
Online Access:https://www.mdpi.com/2072-6694/13/11/2655

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https://www.mdpi.com/2072-6694/13/11/2655

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