β-hydroxybutyrate impairs the directionality of migrating neutrophils through inhibiting the autophagy-dependent degradation of Cdc42 and Rac1 in ketotic cows

β-hydroxybutyrate impairs the directionality of migrating neutrophils through inhibiting the autophagy-dependent degradation of Cdc42 and Rac1 in ketotic cows

ABSTRACT: Dairy cows have high incidence of ketosis during perinatal. According to our previous studies, elevated ketone bodies (mainly β-hydroxybutyrate, BHB) in the peripheral blood are believed to contribute to the impairment of neutrophils mobility and directionality thereby contributing to the...

Full description

Bibliographic Details
Main Authors: Yuchen Yang, Shang Jiang, Jing Yang, Xiancheng Feng, Chao Wang, Kexin Wang, Wenwen Gao, Xiliang Du, Lin Lei, Zhe Wang, Guowen Liu, Yuxiang Song, Xinwei Li
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Journal of Dairy Science
Subjects:
ketosis
immunosuppression
β-hydroxybutyrate
neutrophil
migration directionality
Online Access:http://www.sciencedirect.com/science/article/pii/S0022030223004939

Internet

http://www.sciencedirect.com/science/article/pii/S0022030223004939

Similar Items