Systematic discovery of novel eukaryotic transcriptional regulators using sequence homology independent prediction

Systematic discovery of novel eukaryotic transcriptional regulators using sequence homology independent prediction

Abstract Background The molecular function of a gene is most commonly inferred by sequence similarity. Therefore, genes that lack sufficient sequence similarity to characterized genes (such as certain classes of transcriptional regulators) are difficult to classify using most function prediction alg...

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Bibliographic Details
Main Authors: Flavia Bossi, Jue Fan, Jun Xiao, Lilyana Chandra, Max Shen, Yanniv Dorone, Doris Wagner, Seung Y. Rhee
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Genomics
Subjects:
Genes with unknown function
Transcriptional regulators
Coactivators
Polycomb repressive complex 2
Online Access:http://link.springer.com/article/10.1186/s12864-017-3853-9

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http://link.springer.com/article/10.1186/s12864-017-3853-9

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