Cross-Reactive Fc-Mediated Antibody Responses to Influenza HA Stem Region in Human Sera Following Seasonal Vaccination

Cross-Reactive Fc-Mediated Antibody Responses to Influenza HA Stem Region in Human Sera Following Seasonal Vaccination

<b>Background:</b> Current influenza A vaccines primarily induce neutralizing antibodies targeting the variable hemagglutinin (HA) head domain, limiting their effectiveness against diverse or emerging influenza A virus (IAV) subtypes. The conserved HA stem domain, particularly the long α...

Full description

Bibliographic Details
Main Authors: Ayae Nishiyama, Takuto Nogimori, Yuji Masuta, Tomoka Matsuura, Tetsuo Kase, Kyoko Kondo, Satoko Ohfuji, Yu Nakagama, Natsuko Kaku, Sachie Nakagama, Yuko Nitahara, Yoshimasa Takahashi, Hiroshi Kakeya, Yasutoshi Kido, Wakaba Fukushima, Takuya Yamamoto
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Vaccines
Subjects:
influenza virus
vaccine
antibody-dependent cellular cytotoxicity
antibody-dependent cellular phagocytosis
Online Access:https://www.mdpi.com/2076-393X/13/2/140

Internet

https://www.mdpi.com/2076-393X/13/2/140

Similar Items