The Chromatin Remodeler ATRX: Role and Mechanism in Biology and Cancer

The Chromatin Remodeler ATRX: Role and Mechanism in Biology and Cancer

The alpha-thalassemia mental retardation X-linked (ATRX) syndrome protein is a chromatin remodeling protein that primarily promotes the deposit of H3.3 histone variants in the telomere area. ATRX mutations not only cause ATRX syndrome but also influence development and promote cancer. The primary mo...

Full description

Bibliographic Details
Main Authors: Ying Pang, Xu Chen, Tongjie Ji, Meng Cheng, Rui Wang, Chunyu Zhang, Min Liu, Jing Zhang, Chunlong Zhong
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cancers
Subjects:
alpha-thalassemia mental retardation X-linked syndrome protein (ATRX)
death-domain-associated protein (DAXX)
DNA damage
replication stress
tumorigenesis
Online Access:https://www.mdpi.com/2072-6694/15/8/2228

Internet

https://www.mdpi.com/2072-6694/15/8/2228

Similar Items