Biological Functions and Regulatory Mechanisms of Hypoxia-Inducible Factor-1α in Ischemic Stroke

Biological Functions and Regulatory Mechanisms of Hypoxia-Inducible Factor-1α in Ischemic Stroke

Ischemic stroke is caused by insufficient cerebrovascular blood and oxygen supply. It is a major contributor to death or disability worldwide and has become a heavy societal and clinical burden. To date, effective treatments for ischemic stroke are limited, and innovative therapeutic methods are urg...

Full description

Bibliographic Details
Main Authors: Qianyan He, Yinzhong Ma, Jie Liu, Dianhui Zhang, Jiaxin Ren, Ruoyu Zhao, JunLei Chang, Zhen-Ni Guo, Yi Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Immunology
Subjects:
HIF-1α
ischemic stroke
hypoxia
neurovascular unit
neuroprotection
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.801985/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.801985/full

Similar Items