Cerebral furin deficiency causes hydrocephalus in mice

Cerebral furin deficiency causes hydrocephalus in mice

Furin is a pro-protein convertase that moves between the trans-Golgi network and cell surface in the secretory pathway. We have previously reported that cerebral overexpression of furin promotes cognitive functions in mice. Here, by generating the brain-specific furin conditional knockout (cKO) mice...

Full description

Bibliographic Details
Main Authors: Shiqi Xie, Xiaoyong Xie, Jing Tang, Biao Luo, Jian Chen, Qixin Wen, Jianrong Zhou, Guojun Chen
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-05-01
Series:Genes and Diseases
Subjects:
Astrocyte
Ciliogenesis
Conditional knockout
Ependymal
Furin
Hydrocephalus
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304223002660

Internet

http://www.sciencedirect.com/science/article/pii/S2352304223002660

Similar Items