Cytochrome P450 monooxygenase of Acanthamoeba castellanii participates in resistance to polyhexamethylene biguanide treatment

Cytochrome P450 monooxygenase of Acanthamoeba castellanii participates in resistance to polyhexamethylene biguanide treatment

Acanthamoeba spp. are free-living parasites that can cause severe infections such as granulomatous amoebic encephalitis (GAE) and amoebic keratitis (AK). Polyhexamethylene biguanide (PHMB) is a topical application for AK treatment. However, PHMB is not entirely effective against all Acanthamoeba str...

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Bibliographic Details
Main Authors: Huang Jian-Ming, Ko Pin-Ju, Huang Chao-Li, Wen Po-Wei, Chen Chun-Hsien, Shih Min-Hsiu, Lin Wei-Chen, Huang Fu-Chin
Format: Article
Language:English
Published: EDP Sciences 2021-01-01
Series:Parasite
Subjects:
acanthamoeba
polyhexamethylene biguanide
p450 monooxygenase
amoebic keratitis
Online Access:https://www.parasite-journal.org/articles/parasite/full_html/2021/01/parasite210084/parasite210084.html

Internet

https://www.parasite-journal.org/articles/parasite/full_html/2021/01/parasite210084/parasite210084.html

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