Telomere as a Therapeutic Target in Dedifferentiated Liposarcoma

Telomere as a Therapeutic Target in Dedifferentiated Liposarcoma

Background: Well-differentiated (WD)/dedifferentiated (DD) liposarcoma (LPS) accounts for ~60% of retroperitoneal sarcomas. WDLPS and DDLPS divergently evolve from a common precursor and are both marked by the amplification of the 12q13–q15 region, leading to the abnormal expression of <i>MDM2...

Full description

Bibliographic Details
Main Authors: Irene Alessandrini, Stefano Percio, Eisa Naghshineh, Valentina Zuco, Silvia Stacchiotti, Alessandro Gronchi, Sandro Pasquali, Nadia Zaffaroni, Marco Folini
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cancers
Subjects:
apoptosis
autophagy
dedifferentiated liposarcoma
G-quadruplex
micronuclei
soft tissue sarcoma
Online Access:https://www.mdpi.com/2072-6694/14/11/2624

Internet

https://www.mdpi.com/2072-6694/14/11/2624

Similar Items