Cardiac <i>Hamp</i> mRNA Is Predominantly Expressed in the Right Atrium and Does Not Respond to Iron

Cardiac <i>Hamp</i> mRNA Is Predominantly Expressed in the Right Atrium and Does Not Respond to Iron

Hepcidin is a liver-derived hormone that controls systemic iron traffic. It is also expressed in the heart, where it acts locally. We utilized cell and mouse models to study the regulation, expression, and function of cardiac hepcidin. Hepcidin-encoding <i>Hamp</i> mRNA was induced upon...

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Bibliographic Details
Main Authors: Maria Bigorra Mir, Edouard Charlebois, Sofiya Tsyplenkova, Carine Fillebeen, Kostas Pantopoulos
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
hepcidin
hemojuvelin
ferroportin
iron metabolism
atria
cardiomyocytes
Online Access:https://www.mdpi.com/1422-0067/24/6/5163

Internet

https://www.mdpi.com/1422-0067/24/6/5163

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