Effects of FTY720 on brain neurogenic niches in vitro and after kainic acid-induced injury

Effects of FTY720 on brain neurogenic niches in vitro and after kainic acid-induced injury

Abstract Background FTY720 (fingolimod, Gilenya™) is an oral, blood-brain barrier (BBB)-passing drug approved as immunomodulatory treatment for relapsing-remitting form of the multiple sclerosis (MS). In addition, FTY720 exerts several effects in the central nervous system (CNS), ranging from neurop...

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Bibliographic Details
Main Authors: Raffaela Cipriani, Juan Carlos Chara, Alfredo Rodríguez-Antigüedad, Carlos Matute
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Journal of Neuroinflammation
Subjects:
FTY720
Neural stem cells
Neurogenesis
Oligodendrocyte progenitor cells
Doublecortin
NG2
Online Access:http://link.springer.com/article/10.1186/s12974-017-0922-6

Internet

http://link.springer.com/article/10.1186/s12974-017-0922-6

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