Selenium and the 15kDa Selenoprotein Impact Colorectal Tumorigenesis by Modulating Intestinal Barrier Integrity

Selenium and the 15kDa Selenoprotein Impact Colorectal Tumorigenesis by Modulating Intestinal Barrier Integrity

Selenoproteins play important roles in many cellular functions and biochemical pathways in mammals. Our previous study showed that the deficiency of the 15 kDa selenoprotein (<i>Selenof</i>) significantly reduced the formation of aberrant crypt foci (ACF) in a mouse model of azoxymethane...

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Bibliographic Details
Main Authors: Jessica A. Canter, Sarah E. Ernst, Kristin M. Peters, Bradley A. Carlson, Noelle R. J. Thielman, Lara Grysczyk, Precious Udofe, Yunkai Yu, Liang Cao, Cindy D. Davis, Vadim N. Gladyshev, Dolph L. Hatfield, Petra A. Tsuji
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
Selenof
selenium
selenoprotein
colon cancer
inflammation
barrier integrity
Online Access:https://www.mdpi.com/1422-0067/22/19/10651

Internet

https://www.mdpi.com/1422-0067/22/19/10651

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