Treatment of human acute schistosomiasis with oxamniquine induces an increase in interferon-gamma response to Schistosoma mansoni antigens

Treatment of human acute schistosomiasis with oxamniquine induces an increase in interferon-gamma response to Schistosoma mansoni antigens

Patients with acute schistosomiasis were studied before and after oxamniquine treatment. They had been exposed to cercariae 5 to 9 weeks before, and presented compatible clinical manifestations, eosinophilia, and high levels of total IgE. Interferon-gamma (IFN-gamma) and interleukin-4 were measured...

Full description

Bibliographic Details
Main Authors: Joelma R de Souza, Clarice NL Morais, Marcílio L Aroucha, Paulo JC Miranda, Constança S Barbosa, Ana Lúcia C Domingues, Luiz B Carvalho Júnior, Frederico GC Abath, Silvia ML Montenegro
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2007-03-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Schistosoma mansoni
acute schistosomiasis
oxamniquine
cytokines
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000200017

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000200017

Similar Items