Aryl hydrocarbon receptor modulates stroke-induced astrogliosis and neurogenesis in the adult mouse brain

Aryl hydrocarbon receptor modulates stroke-induced astrogliosis and neurogenesis in the adult mouse brain

Abstract Background The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor activated by environmental agonists and dietary tryptophan metabolites for the immune response and cell cycle regulation. Emerging evidence suggests that AHR activation after acute stroke may play a ro...

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Bibliographic Details
Main Authors: Wan-Ci Chen, Li-Hsin Chang, Shiang-Suo Huang, Yu-Jie Huang, Chun-Lien Chih, Hung-Chih Kuo, Yi-Hsuan Lee, I-Hui Lee
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Journal of Neuroinflammation
Subjects:
Stroke
Aryl hydrocarbon receptor
Gliosis
Neurogenesis
Inflammation
Neural stem cells
Online Access:http://link.springer.com/article/10.1186/s12974-019-1572-7

Internet

http://link.springer.com/article/10.1186/s12974-019-1572-7

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