Moment estimators of relatedness from low-depth whole-genome sequencing data

Moment estimators of relatedness from low-depth whole-genome sequencing data

Abstract Background Estimating relatedness is an important step for many genetic study designs. A variety of methods for estimating coefficients of pairwise relatedness from genotype data have been proposed. Both the kinship coefficient $$\varphi$$ φ and the fraternity coefficient $$\psi$$ ψ for all...

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Bibliographic Details
Main Authors: Anthony F. Herzig, M. Ciullo, FranceGenRef Consortium, A-L. Leutenegger, H. Perdry
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Bioinformatics
Subjects:
Kinship
Fraternity coefficient
Low-depth
Sequencing data
Genotype likelihoods
Moment estimators
Online Access:https://doi.org/10.1186/s12859-022-04795-8

Internet

https://doi.org/10.1186/s12859-022-04795-8

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