HPV16 E6 enhances the radiosensitivity in HPV-positive human head and neck squamous cell carcinoma by regulating the miR-27a-3p/SMG1 axis

HPV16 E6 enhances the radiosensitivity in HPV-positive human head and neck squamous cell carcinoma by regulating the miR-27a-3p/SMG1 axis

Abstract Background Head and neck squamous cell carcinoma (HNSCC) is the 6th most common malignant cancer type worldwide. Radiosensitivity has been shown to be significantly increased in patients with human papillomavirus (HPV)-positive HNSCC compared with HPV-negative patients. However, the clinica...

Full description

Bibliographic Details
Main Authors: Dan Long, Li Xu, Zeyi Deng, Dandan Guo, Yangchun Zhang, Zhaohui Liu, Chunlin Zhang
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Infectious Agents and Cancer
Subjects:
Head and neck cancer
HPV16
Radiosensitivity
E6
miR-27a-3p
SMG1
Online Access:https://doi.org/10.1186/s13027-021-00397-w

Internet

https://doi.org/10.1186/s13027-021-00397-w

Similar Items