DNA methylome, R-loop and clinical exome profiling of patients with sporadic amyotrophic lateral sclerosis

DNA methylome, R-loop and clinical exome profiling of patients with sporadic amyotrophic lateral sclerosis

Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the death of motor neurons, the aetiology of which is essentially unknown. Here, we present an integrative epigenomic study in blood samples from seven clinically characterised sporadic ALS patients t...

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Bibliographic Details
Main Authors: Orsolya Feró, Dóra Varga, Éva Nagy, Zsolt Karányi, Éva Sipos, József Engelhardt, Nóra Török, István Balogh, Borbála Vető, István Likó, Ábel Fóthi, Zoltán Szabó, Gábor Halmos, László Vécsei, Tamás Arányi, Lóránt Székvölgyi
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-024-02985-y

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https://doi.org/10.1038/s41597-024-02985-y

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