Upregulation of cell surface GD3 ganglioside phenotype is associated with human melanoma brain metastasis

Upregulation of cell surface GD3 ganglioside phenotype is associated with human melanoma brain metastasis

Melanoma metastasis to the brain is one of the most frequent extracranial brain tumors. Cell surface gangliosides are elevated in melanoma metastasis; however, the metabolic regulatory mechanisms that govern these specific changes are poorly understood in melanoma particularly brain metastases (MBM)...

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Bibliographic Details
Main Authors: Romela Irene Ramos, Matias A. Bustos, Jinfeng Wu, Peter Jones, Shu Ching Chang, Eiji Kiyohara, Kevin Tran, Xiaoqing Zhang, Stacey L. Stern, Sivan Izraely, Orit Sagi‐Assif, Isaac P. Witz, Michael A. Davies, Gordon B. Mills, Daniel F. Kelly, Reiko F. Irie, Dave S. B. Hoon
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Molecular Oncology
Subjects:
gangliosides
GD3
lymph node
melanoma brain metastasis
NF‐κB
ST8SIA1
Online Access:https://doi.org/10.1002/1878-0261.12702

Internet

https://doi.org/10.1002/1878-0261.12702

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