Wilms’ Tumor 1-Associated Protein Contributes to Chemo-Resistance to Cisplatin Through the Wnt/β-Catenin Pathway in Endometrial Cancer

Wilms’ Tumor 1-Associated Protein Contributes to Chemo-Resistance to Cisplatin Through the Wnt/β-Catenin Pathway in Endometrial Cancer

BackgroundCisplatin remains the mainstay of endometrial cancer (EC) chemotherapy. Wilms’ tumor 1-associated protein (WTAP), playing a critical role in transcriptional and post-transcriptional regulation, has been reported as an oncogene, and its expression is elevated in multiple types of human tumo...

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Bibliographic Details
Main Authors: Wenli Xie, Naifu Liu, Xiangyu Wang, Ling Wei, Wenyan Xie, Xiugui Sheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
Wilms’ tumor 1-associated protein
endometrial cancer
cisplatin
chemo-sensitivity
Wnt
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.598344/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.598344/full

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