Aminoprocalcitonin protects against hippocampal neuronal death via preserving oxidative phosphorylation in refractory status epilepticus

Aminoprocalcitonin protects against hippocampal neuronal death via preserving oxidative phosphorylation in refractory status epilepticus

Abstract Refractory status epilepticus (RSE) is a neurological emergency where sustaining seizure causes severe neuronal death. Currently, there is no available neuroprotectant effective in RSE. Aminoprocalcitonin (NPCT) is a conserved peptide cleaved from procalcitonin, but its distribution and fun...

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Bibliographic Details
Main Authors: Changgeng Song, Jingjing Zhao, Jianmin Hao, Dan Mi, Jiajia Zhang, Yingying Liu, Shengxi Wu, Fang Gao, Wen Jiang
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01445-7

Internet

https://doi.org/10.1038/s41420-023-01445-7

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